JOB PURPOSE: 

The Chanjo Hub Project is a groundbreaking initiative focused on the development and manufacturing of a candidate malaria vaccine using egg production in Ghana, coupled with innovative mRNA technology in Kenya. With the aim of combating malaria, our project brings together a diverse team of experts and collaborators to advance research and development in the field of malaria... immunisation.

Description: 
REPORTS TO:  Principal Investigator (PhD – Postdocs and Research Fellows)
DIRECTLY SUPERVISES: Field workers, interns etc
INDIRECTLY SUPERVISES: None.
BUDGET AND RESOURCE RESPONSIBILITY:   Develop project budget
JOB DIMENSIONS: 

We are seeking a highly motivated and detail-oriented Assistant Research Officer (ARO) to join our team and contribute to the regulatory strengthening aspects of the Chanjo Hub Project. The successful candidate will play a crucial role in ensuring compliance with regulatory requirements for the manufacturing of the malaria vaccine by egg production in Ghana and by mRNA in Kenya. This role will involve working with internal teams in both countries to ensure regulatory compliance, developing institutional development plans for regulatory strengthening, collaborating with National Regulatory Authorities (NRAs) to facilitate process evaluations, and evaluating the readiness or strengthening needs of National Regulatory Authorities in alignment with the WHO NRA maturity levels.

KEY RESPONSIBILITIES:
Institutional Development Plans:

Work with internal teams in Kenya and Ghana to develop vaccine regulatory institutional development plans.
Assist in the implementation of strategies to enhance regulatory capabilities within the organisations.

Regulatory Compliance Oversight:

Collaborate with internal teams in Kenya and Ghana to ensure compliance with local and international regulatory requirements for mRNA vaccine production and egg production, respectively.
Provide guidance and support to internal teams to navigate regulatory processes effectively.

Project Coordination:

Liaise with internal teams to integrate regulatory considerations into project timelines.
Coordinate with external partners and vendors (USP, GIZ, PPB and Ghana FDA) involved in the regulatory process.
Create reports and update grant reports in liaison with CHANJO hub program manager.

National Regulatory Authority Collaboration:

Work with USP to identify and document NRA gaps facilitating and providing input in meetings and workshops.
Through USP, facilitate National Regulatory Authorities in Kenya and Ghana’s understanding of the vaccine production and egg production processes.
Contribute to USP plans to evaluate National Regulatory Authority readiness or strengthening needs, in alignment with WHO maturity levels.

Documentation and Reporting:

Maintain accurate and up-to-date documentation of all regulatory activities of Chanjo hub.
Prepare and submit regular reports on regulatory progress and milestones.
Create and maintain records of meeting minutes, workshop and audit reports.

QUALIFICATIONS:

Minimum Bachelor's degree in a relevant scientific field (biology, biochemistry, pharmaceutical sciences, etc.).
Minimum two(2) years prior experience in regulatory affairs, preferably in the pharmaceutical or vaccine development industry.

DESIRABLE CRITERIA:

Knowledge of mRNA and egg-based vaccine production processes and regulatory requirements.
Familiarity with WHO maturity levels for regulatory systems.
Strong organisational and project management skills.
Excellent communication and interpersonal skills

COMPETENCIES:

Demonstrate high levels of integrity and confidentiality 
Excellent interpersonal, written, presentation and communication skills 
Basic analytical, problem solving and critical thinking skills; 
Team working and ability to work in diverse teams 
Flexibility, adaptability, multi-tasking and attention to detail
 more
  • Research
JOB PURPOSE: 

Welcome to the exciting opportunity to contribute to groundbreaking research at the KEMRI-Wellcome Trust Research Programme (KWTRP), a leading research centre in Africa dedicated to investigating the primary causes of ill health and the development of health care systems on the continent. At KWTRP, we are not only committed to advancing scientific knowledge but also to fostering... local research leadership.
Part of the research portfolio of the Population and Health Impact Surveillance Research Unit (PHISG) and the Health Services Unit at KWTRP Nairobi is to undertake research into the relationships between health outcomes and access to health services, the ecological defined phenotypes of severe disease and determinants of hospitalisation and death in childhood.
The new Research Officer position will join the Population and Health Impact Surveillance Research Unit in Nairobi and will be supervised by Prof. Emelda Okiro and co-supervised by Prof Bob Snow. The Research Officer will be expected to provide statistical support to the PHISG. It is also expected that the appointed RO will build an independent line of enquiry related to hospital access and in-patient outcomes, helping the wide group understand optimised catchment areas for emergency care and marginalised, poor hospital access populations.

We, therefore, welcome applications from those wishing to develop their skills and a career in medical statistics, geospatial analysis and the use of hospital data in epidemiology.
Description: 
REPORTS TO: Study PI and Study Supervisor
DIRECT REPORTS: None
INDIRECT REPORTS: None
BUDGET AND RESOURCE RESPONSIBILITY:  Responsible for allocated hardware and software.
KEY RESPONSIBILITIES:
For the Population and Health Impact Surveillance Research Unit and under the direction of the supervisors to:

Provide statistical and R coding support to PHISG
Build and check fidelities of locational data of hospital admissions in Western Kenya and Kilifi
Undertake geospatial analysis of data to understand the geographic distribution of different hospital admissions, linked to ecological and malaria risk factors
Publish independent research findings in peer reviewed journals and support other publications in the PHISG
Contribute to the wider scientific activities of the Population and Health Impact Surveillance Research Unit, the Health Services Unit and the Nairobi Programme of KEMRI-Wellcome in Kenya
And any other duties that may be assigned from time to time.

QUALIFICATIONS:
The successful applicant will have:
CRITERIA:
The successful applicant will have:

Recognised Postgraduate qualification (Masters) relevant to the field of statistics or epidemiology
At lease 3 years related working experience.
A track record in understanding statistical methods related to health care access.
A track record in handling large health data and statistical packages including R
Published in peer reviewed journals at least one first author paper, and co-authored at least three publications
Highly developed oral and written communication skills
Experience in undertaking research in a cross-cultural context
Demonstrated interest in public health and demonstrated knowledge and working experience of Kenyan Health system, added advantage.

COMPETENCIES:

Prior experience of geospatial analyses with recognised software (e.g. ArcGIS) is highly desirable.
Experience in use of STATA and / or ‘R’ for analysis of health data and/or experience of computer programming languages.
Have high energy, clear goal orientation and a strong work ethic.
Strong organisation/programme management skills with the ability to prioritise workloads and work within tight deadlines
Ability to write clearly for a scientific audience and to present clearly to non-academic audiences
Ability to work independently and collaboratively in a team environment and to multi-task
 more
  • Research
JOB PURPOSE: 
This is a middle level position for this opening with higher levels of Autonomy, Influence and Complexity. Following SFIA 6 framework, this position is rated at Level 4.  The candidate would advise on the design, creation, testing and documenting of new and amended programs from supplied specifications to meet programme’s business objectives in accordance with agreed... standards.
Description: 
REPORTS TO: Software Development Manager
BUDGET AND FINANCIAL RESPONSIBILITY: Ensure and advise on software systems specifications required to meet budgetary constraints.
KEY RESPONSIBILITIES:

Analyze and propose solutions to user and technical requirements for both backend and frontend to ensure enhanced user experience.
Review with the Software Development Manager the Software development framework and processes.
Designs, codes, tests, corrects, and documents large and/or complex programs which span across the enterprise using agreed standards and tools, to achieve a well-engineered result.
Conducts reviews of supplied specifications, with others as appropriate.
Takes part in reviews of own work and leads reviews of colleagues’ work.
Working with Database Administrators and System Administrators to ensure optimal systems performance in the programme.
Expected to conduct system analysis of systems as directed by SDM.
Responding promptly and professionally to bug reports.
To participate in the execution and support for all IT Projects        
Expected to conduct system analysis and development, with limited support from professional staff, to keep our systems current with changing technologies.
Responsible for development of new programs, analyzes current programs and processes, and making recommendations that yield a more cost-effective product.
Document code consistently throughout the development process by listing a description of the program, special instructions, and any changes made in database tables on procedural.
Observe Change Control, Event, Configuration, and Incident management as minimum business processes when executing Service Design and Transition
Adhere to IT development standards on naming conventions, code testing, release management, source code control, and collaboration.
Carry out research and development on enterprise applications as directed by IT management to meet various programme needs.
Respond to business-as-usual system requests for complex systems.
Mentoring Software developers and other technical staff.

QUALIFICATIONS 

Degree in Computer Science or related fields.
Minimum 5 years of Software development work experience.
Proficient in PHP or Microsoft .Net programming languages and frameworks and related Open-Source Technologies.
Strong understanding of the software development life cycle.
Have a good mastery of software engineering best practices.
Experience and working knowledge of database management systems and SQL.
Experience in web Services protocols such as REST, SOAP and API design for extensibility and portability.

DESIRABLE:

Programmer Certification (e.g. MCSD, ZEND PHP, Mobile Apps Dev) with evidence of the exam certificate done by an authorised testing body, i.e. Pearson VUE, Prometric etc.)
Ability to develop Enterprise solutions using Microsoft power-platform.
Experience with Scrum/Agile development methodologies
Experience of working in a research establishment
Mobile Applications Development.
Database Sever administration.

COMPETENCIES

Ability to multi-task and stay organized in a dynamic work environment.
Expert knowledge of data structures and algorithms.
Expert knowledge of computer program design methods and techniques.
Excellent skills in problem solving, debugging, troubleshooting and maintenance of software applications.
Ability to learn new programming languages quickly.
Expert knowledge of writing program documentation.
Strong communications skills, both in writing and speaking.
Ability to work with technical and non-technical business owners to get things done.
Proficient in source code and version control.
Have a creative mind.

PHYSICAL ENVIRONMENT/CONDITIONS:

Based at the KEMRI/Wellcome Trust Research Programme in Kilifi, Kenya.
 more
  • ICT
  • Computer
JOB PURPOSE: 
To be a co-lead on the day-to day activities of the VANGUARD Community Study which involves overseeing a community survey and collection of biological samples across the VANGUARD study sites in Kenya.
The post holder will coordinate the community survey and laboratory research activities in the study sites and be the key liaison with the VANGUARD Uganda team. He/she will contribute... to planning of field work related to the community survey and laboratory related activities including field-laboratory liaison, samples/specimen management, data analysis and preparation of publications.
Description: 
REPORTS TO: Principal Investigators and Co-PIs
DIRECTLY SUPERVISES: Field Staff/Field Workers
INDIRECTLY SUPERVISES: Laboratory Technologist
BUDGET AND FINANCIAL RESPONSIBILITY: Work planning and task allocation, requisition and procurement of supplies, and consumables and ensuring sensible use of resources.
JOB DIMENSIONS:
The KEMRI-Wellcome Trust Collaborative Research Programme (KWTRP) conducts research on diseases with the highest burden in developing countries for which it is recognised internationally within the fields of international public health, clinical tropical medicine, epidemiology, and immunology. The programme aims to maximise opportunities for learning and training to maintain a cadre of highly skilled and experienced staff from all disciplines.
The Vanguard NIHR project
Vaccines are among the successful public health interventions. However, not all communities benefit equally. Various factors, including  biological, social, health system and political factors, interact to reduce vaccine effectiveness and impact on vulnerable communities. Populations living in low-income or rural areas have been shown to have impaired vaccine immunogenicity, but little is known about the underlying biological mechanisms. The Vaccines for vulnerable people in Africa (VAnguard) project aims to identify modifiable structural, social, and biological determinants of impaired vaccine impact in vulnerable African communities and develop integrated strategies to address them.
The post holder will work together with a Research Officer (Social Science) to co-lead Work Package 4 with supervision from the VANGUARD PIs (Kenya and Uganda). The purpose of WP4 is to plan and implement field investigations (community surveys and qualitative studies) to explore structural, social and biological determinants impairing vaccine impact. The preparatory phase will involve consultation with collaborators/stakeholders and stakeholder mapping and engagement at County and community levels. The post holder will organise field research teams to conduct community surveys including the collection of questionnaire data and biological samples.
The post holder will need to be self-sufficient and be able to work with minimal supervision against demanding yet, often unpredictable timelines.  The post is mentally demanding and involves a high level of communication. The post holder may also be required to contribute to other VAnguard Work packages.
KEY RESPONSIBILITIES:

Work with the Principal Investigator and other relevant staff members to prepare research and field work plans in liaison with other teams such as KHDSS and laboratory.
Co- lead the execution of the Vanguard community study – to include setting up the study, preparing the field work plans for the study sites, identifying resource requirements, development and documentation of protocols and training staff on the same etc.
Carry out desktop research/ literature reviews and prepare/ draft write-ups as may be required for inclusion in/ to support proposals, presentations/seminars and publications.
Coordinate and participate in the collection and processing of biological samples as well as data compilation and analysis of study data/samples, and ensure all related records and reports are handled and managed in line with study protocols.
Perform a range of quality assurance activities within the study.
Liaise with Vanguard (Uganda) statistics and data management teams to ensure data entry and storage is appropriate and compliant with prevailing procedures.
Carry out data analysis and interpretation and provide relevant matrices/ information including statistics, summaries, charts, graphs, reports etc.
Prepare and submit draft reports as required including activity reports, project progress reports etc.
Participate in preparation of submissions and correspondences with Institutional Ethics Committees and other regulatory bodies.
Manage study resources (including HR, equipment & facilities), ensuring efficient and ethical usage and complying with all research sponsor/funder accountability requirements.
Support Work package 5 in the implementation of stakeholder, Community and Public Engagement and involvement of survey activities.
Support laboratory technician in the study communities as required and with procurement of necessary laboratory equipment and supplies and development and implementation of laboratory analysis plans and standard operating procedures.

QUALIFICATIONS 

A BSc degree in Biomedical Sciences, or another related field and a Master’s degree in a relevant subject added advantage.
Minimum 2 years experience including management of field-based research
Computer literacy with proficiency in Microsoft applications
Must have prior experience of running field-based studies
Data management and basic statistical skills
Good writing skills including evidence of publications/reports

 COMPETENCIES:

Good planning, organisation and coordination skills and attention to detail
Ability to take and follow instructions, initiative, keen to learn and proactive with the ability to work under minimal supervision.
Experience in engaging collaborators and stakeholders e.g. community and county Health stakeholders
Experience/Competence in running surveillance studies involving collecting survey data and biological samples.
Flexibility, adaptability, ability to multi-task
Confidentiality and integrity
Excellent interpersonal and communication skills, team working and ability to work in a multicultural environment.

PHYSICAL ENVIRONMENT/CONDITIONS:

Based at the KEMRI/Wellcome Trust Research Programme in Kilifi, Kenya.
Be available to work out of hours if necessary.
Exposure to materials considered infectious and/or biohazards.
 more
  • Research
JOB PURPOSE: 
Maintain and enhance the security policies and standards to ensure all issues of security, risk and performance are fully addressed and to provide Information Security services to the organization
Description: 
Reports to: IT Risk and Security Manager
Key Responsibilities

Audit and constant monitoring of all systems, internal and external information security infrastructure,... including but not limited to Firewalls, Proxy Servers, Anti-Virus, Anti-Malware, Intrusion Detection Software to provide optimum security, performance, and availability.
Perform vulnerability assessment and penetration testing on KWTRP infrastructure and applications to ensure that they are secure from external or internal hacking attempts.
Provide technical security reports to the Senior IT Managers and IT Risk and Security Manager.
Develop IT Security Policies, Minimum Baseline Security Standards in line with industry best practices and technologies, commensurate with risk and regulatory requirements and implementing the same cost effectively.
Provide technical security related support to new projects from inception through to successful implementation.
Support the implementation of procedural, operational and technical Security Architecture enhancements.
Ensure constant monitoring of the environment for security vulnerabilities or breaches.
Ensure processes and procedures are in place to maintain security and integrity of the Information & Technology environment and that these are adhered to.
Establish stringent access control management on user account creation, maintenance and termination on operating systems, applications, and databases to ensure information systems security.
Train users and promote security awareness to ensure system security and to improve server and network efficiency.
Manage IT Security Incidences, Problems, Events and Service requests, Raising Change Requests to transit resolves to technology problems. Transiting technology products in the Service Portfolio, retiring and replacing them at the end of the lifecycle.
To carry out project-based work to implement new Security solutions.
Develops and maintains the patch management process and ensures all patches are in place.
Updates the IT risk register on a regular basis.
Updates the IT vulnerability register on a regular basis.
Provides 1st and 2nd line support for IT Security technical user issues.
Supports the Disaster recovery and testing plans.
Provide level 2 and 3 soc analyst support.
Manage IT security tools such as Vulnerability management, EDR and PAM
Carry out IT risk assessment on a scheduled basis.
Provide support in the implementation of information security programs as per strategy requirements.

Job Specification

A Bachelor of Science in Computing or related degree from a recognised University.
Internationally recognized IT security certification such as CISM, CISSP, CISA, CASP, ISO 27001 Implementer and or Auditor, MCSE CEH or Security+.
At least 5 years’ experience in Information Technology, 3 of which must be in IT Security function with hands on experience in the following areas listed below:
IT risk and Security compliance solutions
Cloud IT Security applications
Software / application and security architectures
IPS and vulnerability Testing tools
Active Directory management
Good understanding of endpoint solutions
Understanding of the perimeter wall solution
IT security monitoring
Good understanding of IT security tools such as SIEM, PAM and DAM

Desirable

IT Security on O365, operating systems and databases in an heterogenous environment (UNIX, Microsoft, Oracle, SQL, Open source)
Wide knowledge of web security architecture.
Knowledge and skills on encryption, VPN
Excellent verbal and written communication skills with technical and non-technical staff, end-users, and senior management.
Strong teamwork skills to maintain strong working relationships, within and outside IT to develop a results-oriented work environment.
Excellent follow-up skills to see tasks through to resolution and communicate problem status to end users such as notification of completion, notification of delay, and explaining rationale.
Excellent analytical solving skills.
Excellent organizational skills, prioritizing and managing multiple tasks.
Offer and accept feedback and constructive suggestions.

Competencies:

Demonstrate high levels of integrity.
Analytical and problem-solving skills
Ability to multi-task and stay organized in a dynamic work environment.
Ability to provide adhoc support to different database environments.
Strong interpersonal and communications skills, both in writing and oral
Logical diagnostic skills and ability to exercise good judgement in the resolution of problems.
Ability to learn new programming languages quickly.
Ability to write, edit, and debug computer programs to achieve desired output.
Strong understanding of the software development cycle.
Good presentation skills.
 more
  • ICT
  • Computer
JOB PURPOSE: 
The incumbent will largely be involved in performing cell sorting and phenotypic analysis. Ability to perform and troubleshoot basic flow cytometry and cell sorting procedures will be an added advantage. The job is based at KWTRP in Kilifi, Kenya but the incumbent will also interact and work closely with IAVI collaborating institutions.
Description: 
REPORTS TO: Group lead Postdoc... and to the Principal Investigator
DIRECTLY SUPERVISES: None
BUDGET AND FINANCIAL RESPONSIBILITY: Will be responsible for a laptop, data storage and together with the PI, manage budget allocated for flow cytometry analysis.
JOB DIMENSIONS:
KEMRI-Wellcome Trust Research Programme (KWTRP) is one of the leading research centres in Africa. The Programme engages in a wide range of research on the main causes of ill health in Africa. We are seeking to appoint an assistant research officer or research officer in the field of immunology to work in the Biosciences department. The successful candidate will be part of a research team seeking to understand HIV B-cell biology to inform HIV vaccine development. The candidate will principally support various research activities by performing cell sorting and phenotypic characterization using flow cytometry. This work is part of a five-year (2022 - 2026) collaborative programme with IAVI and several clinical research centres in Africa and is funded by USAID. The incumbent will have an opportunity to interact and work as part of the larger immunology analysis team within the IAVI consortium.
KEY RESPONSIBILITIES:

Perform daily maintenance of the flow cytometers, regular Quality Control and co-ordination with BD field service team for machine servicing and repair.
Design and test flow cytometry analysis panels.
Perform flow cytometry and cell sorting for clinical trial analysis and exploratory research projects.
Undergo extensive training in flow cytometry (both software and hardware) and participate in knowledge transfer to the research team.
Lead the trouble shooting process for any arising flow cytometry technical issues.
Collate flow cytometry data generated and provide summaries of the same.
Manage the inventory and procurement of flowcytometry reagents and consumables.
Ensure that all work done complies with the applicable regulations concerning biohazards, data privacy, Good Clinical and Laboratory Practice and maintain all documentation.
And any other duties that may be assigned from time to time.

QUALIFICATION:

Bachelor’s degree in Biological sciences,
Extensive hands-on experience in flow cytometry or a Masters’ degree in Immunology will be an added advantage.
Experience in using Flowjo or any other flow cytometry analysis package.
Experience in using various analytical packages such as STATA and R

COMPETENCIES:

Keen interest in research
Excellent analytical and quantitative skills
Excellent interpersonal and communication skills
Ability to present and summarise results for reporting and publication.
Ability to work independently with minimal supervision.
Team working skills with the ability to work in a multi-cultural setting.

PHYSICAL ENVIRONMENT:

Based at the KEMRI/Wellcome Trust Research Programme in Kilifi, Kenya but be flexible to travel to other partner or collaborating institutions.
Be available to work out of hours if necessary.
Exposure to materials considered infectious and/or biohazards.
 more
  • Data
  • Business Analysis and AI
JOB PURPOSE: 
KEMRI-Wellcome Trust Research Programme (KWTRP) is one of the leading research centres in Africa. The Programme engages in a wide range of research on the main causes of ill health in Africa. We are seeking to appoint a research officer or assistant in the field of bioinformatics or molecular biology to work in the Biosciences department. The successful candidate will be part of a... research team seeking to understand HIV B-cell biology to inform HIV vaccine development. The candidate will be involved in bioinformatics analysis of HIV-antigen specific immunoglobulin gene usage and naïve B cell repertoires mainly in African populations. The incumbent will also provide bioinformatics support for other ongoing immunological work within the group. He/she will require solid knowledge of bioinformatics, ability to write and execute codes and develop custom analysis suites for projects. Additional knowledge in molecular biology techniques will be an added advantage. This work is part of a five-year (2022 - 2026) collaborative programme with IAVI and several clinical research centres in Africa and is funded by USAID. The incumbent will have an opportunity to interact and work as part of the larger bioinformatics team within the IAVI consortium.
Description: 
REPORTS TO: Group lead Postdoc and to the Principal Investigator
BUDGET AND FINANCIAL RESPONSIBILITY: Will be responsible for a laptop, data storage and together with the PI, manage budget allocated for bioinformatics analysis.
JOB DIMENSIONS:
KEMRI-Wellcome Trust Research Programme (KWTRP) is one of the leading research centres in Africa. The Programme engages in a wide range of research on the main causes of ill health in Africa. We are seeking to appoint a research officer or assistant in the field of bioinformatics or molecular biology to work in the Biosciences department. The successful candidate will be part of a research team seeking to understand HIV B-cell biology to inform HIV vaccine development. The candidate will be involved in bioinformatics analysis of HIV-antigen specific immunoglobulin gene usage and naïve B cell repertoires mainly in African populations. The incumbent will also provide bioinformatics support for other ongoing immunological work within the group. He/she will require solid knowledge of bioinformatics, ability to write and execute codes and develop custom analysis suites for projects. Additional knowledge in molecular biology techniques will be an added advantage. This work is part of a five-year (2022 - 2026) collaborative programme with IAVI and several clinical research centres in Africa and is funded by USAID. The incumbent will have an opportunity to interact and work as part of the larger bioinformatics team within the IAVI consortium.
KEY RESPONSIBILITIES:

Perform bioinformatics analysis of large sequencing data sets generated on diverse platforms (NextSeq, MiSeq and NovaSeq).
Co-ordinate data transfer, processing and analysis with collaborators.
Participate in technology transfer from collaborating laboratories.
Participate in the design of exploratory analysis approaches and bioinformatics pipelines. 
Perform basic molecular biology procedures to generate sequencing libraries.
Present project results at different forums.
Contribute to the writing of scientific manuscripts.
Ensure that all work done complies with the applicable regulations concerning biohazards, data privacy, Good Clinical and Laboratory Practice and maintain all documentation.
And any other duties that may be assigned from time to time.

QUALIFICATION:

Bachelor’s degree in Molecular Biology or Bioinformatics
Extensive hands-on experience in Bioinformatics and computational analysis or a Masters’ degree in Bioinformatics/Data science will be an added advantage.
Proficiency in programming in Python and software development stacks
Proficiency with the Pandas Data Library and Jupiter Software Ecosystem
Experience in analysing large next-generation sequencing data.
Experience in using various analytical packages such as STATA and R

COMPETENCIES:

Keen interest in research
Excellent analytical and quantitative skills
Excellent interpersonal and communication skills
Ability to present and summarise results for reporting and publication.
Ability to work independently with minimal supervision.
Team working skills with the ability to work in a multi-cultural setting.

PHYSICAL ENVIRONMENT:

Based at the KEMRI/Wellcome Trust Research Programme in Kilifi, Kenya but be flexible to travel to other partner or collaborating institutions.
Be available to work out of hours if necessary.
Exposure to materials considered infectious and/or biohazards.
 more
  • Data
  • Business Analysis and AI
JOB PURPOSE: 
The research officer will be responsible for 1) Supporting a body of work focused on examining healthcare priority setting in Kenya the broader African region, 2) support the a project focused on the use of economic evidence in vaccine decision-making, 3) Conduct health technology assessments in collaboration with government.
Description: 
REPORTS TO:  Study PI and Study... Supervisor.
DIRECTLY SUPERVISES: None
INDIRECTLY SUPERVISES: None
BUDGET AND RESOURCE RESPONSIBILITY:  None
JOB DIMENSIONS:
The primary responsibility will be to conduct economic evaluations to inform healthcare priority-setting decisions.
KEY RESPONSIBILITIES:
For the Health Economics Research Unit (HERU) to:

Develop research proposals for ethics and scientific review
Lead the implementation of studies once ethics review has been obtained
Lead the analysis and write-up of study findings
Support HERU policy engagement initiatives
Develop grant applications for funding
And any other duties that may be assigned from time to time.

QUALIFICATIONS:
The successful applicant will have:

A Bachelor’s a health-related subject
A masters in health Economics, pharmaco-economics, or pharmaco-epidemiology
At least three years related working experience in Research covering health economics.
Experience and skills in health technology assessments (including skills in costing, and cost-effectiveness analysis of healthcare interventions including using modelling approaches such as decision tree and markov models, budget impact analysis, and evidence synthesis).
Strong quantitative data analysis skills using R and Stata as a minimum.

Desirable Criteria:

Excellent organisational and communication skills

COMPETENCIES:

Good writing skills
Good presentation skills
Excellent interpersonal and communication skills a meticulous approach to documentation (including word processing and spreadsheet skills)
Team working and ability to work in a multi-cultural environment
Ability to work with limited supervision and meet deadlines
 more
  • Research
JOB PURPOSE: 
This role is responsible for development of databases in the environment in accordance to the set standards to meet business objectives. Work includes a broad range of complex technical or professional activities, in a variety of contexts. Investigates, defines and resolves complex issues.
Description: 
Reports to: Software Development Manager
Direct Reports: None
Key... Responsibilities

Administer database management system support activities for operational database systems. 2. Gather requirements, design-build, and implement study databases and data collection tools
Evaluate potential solutions, and demonstrate, install and commission selected products.
Translate object and data models into appropriate database schemas within design constraints. 
Integrate data across applications and DBMSs.
Set data constraints and perform data cleanup to ensure data quality.
Facilitate database development and implementation processes;
Liaise with developers on development project requirements and implement physical database structures.
Develop basic knowledge of database concepts, object and data modelling techniques and design principles.
Assesses proposed changes to objects and data structures and implement changes in physical databases. 
Interpret installation standards to meet project needs and produces database components as required; 
Ensure data security by controlling data access through user authentication and connecting applications.
Develop, manage and test back-up and recovery plans.
Capacity planning by projecting resource utilization;
Monitor performance and manage parameters to provide fast responses to front-end users;
Conduct database backup, storage and archiving; and
Writing database documentation, including data standards, procedures and definitions for the data dictionary (metadata).
Improve and document the technical processes around application support (using Confluence)

Financial Responsibility: None
Minimum Requirements

Bachelor’s degree computer science or in related specialization of study
Minimum 3 years’ experience in database management in environments with Opensource SQL database (MySQL/Maria DB, PostgreSQL). 
Experience in with different database environments and integrating them with web and mobile applications
Familiarity with architecture styles/APIs (REST, RPC)
Knowledge and experience working with agile methodologies.
Familiarity with secure coding standards.
Experience in patching, upgrades, Database hardening, password management and vulnerability management

Desirable 

At least one DBA certification e.g., OCA, MYSQL, MCSA
Experience in Electronic Data Collection systems such e.g., Redcap, ODK, Open Clinica
Experience in working in a research institution and support for clinical applications.
Experience in supporting Microsoft Navision for end users.
Experience in working with SharePoint, power BI, power automate and power apps.

Competencies:

Demonstrate high levels of integrity
Analytical and problem-solving skills
Ability to multi-task and stay organized in a dynamic work environment
Ability to provide adhoc support to different database environments
Strong interpersonal and communications skills, both in writing and oral
Logical diagnostic skills and ability to exercise good judgement in the resolution of problems
Ability to learn new programming languages quickly.
Ability to write, edit, and debug computer programs to achieve desired output.
Strong understanding of the software development cycle.
Good presentation skills;
 more
  • ICT
  • Computer
JOB PURPOSE: 
The overall purpose of this post is to undertake research under the human infection (challenge) platform. This will need to be undertaken under good clinical practice ensuring compliance with regulatory, statutory and programme policies including other related clinical and/or research activities and execution of research studies.
The post holder will be responsible for day-to-day... research activities, develop research ideas, and oversee a team of staff. The post holder will work as lead on specific area of work; contribute to tasks preparatory to the project(s), where applicable, to tasks including developing and submitting protocols, developing study work plans, organising, and conducting training for project-specific staff; and ensure compliance of all study staff to good practices and procedures. Although these are the primary responsibilities, the post-holder will also be involved in higher level responsibilities for ensuring all activities and procedures are carried out to quality standards, managing, and leading a team whilst expected to share the load and as guided by the PI.
This post is open to qualified PhD holders in a relevant field with research experience and will be funded for a three-year period. The post-holder is expected to develop research methods and to execute programme management as well as roles in data management, sample/specimen management, data analysis, and report writing and scientific dissemination through publication writing and presentations. The post is demanding, involving attention to detail and timescales, and strong engagement with various stakeholders and collaborators
Description: 
JOB DIMENSIONS:
The KEMRI-Wellcome Trust Research Programme (KWTRP) conducts high quality research on diseases with the highest burden in developing countries. The programme is recognised internationally within the fields of international public health, clinical tropical medicine, epidemiology, and immunology. The programme aims to maximise opportunities for learning and training to maintain a cadre of highly skilled and experienced staff from all disciplines.
The human infection (challenge) platform currently comprises of conducting clinical trials in two disease areas, malaria and Shigella with the aim of aim of accelerating vaccine development through evaluation of investigational products such as vaccines, identifying correlates of protection and/or correlates of immunity, and understanding of naturally acquired immunity. This involves the deliberate infection of healthy volunteers with infection causing agents (e.g., malaria and Shigella).
The post holder will need to be self-sufficient and be able to work with minimal supervision against demanding yet often unpredictable timelines. The post is mentally demanding and involves a high level of communication. The post holder may also be required to contribute to other linked projects.
The post-holder will be based in Kilifi working within an experienced team and research group.
REPORTS TO: Principal investigator
DIRECTLY SUPERVISES: Key team members for the designated role
INDIRECTLY SUPERVISES: None
BUDGET RESPONSIBILITY: Will be responsible for managing budget allocated to work activities, work planning and task allocation, requisition and procurement of supplies, consumables and ensuring sensible use of resources.
KEY RESPONSIBILITIES:

Independently oversee and coordinate all activities according to GCP and protocol requirements.
Prepare and execute research plans in liaison with other study teams including international collaborating partners.
Take the lead in/contribute to study/clinical trial set up, identification of resource requirements, documentation of protocols, and staff training and as required.
Supervise and mentor other study team members.
Lead the collection, processing, compilation, and analysis of study data/samples and ensure all related records and reports are handled and managed in line with study protocols.
Prepare, analyse, and present research summaries to Kilifi County public health staff, international collaborators, sponsors and at international conferences and meetings.
KEY RESPONSIBILITIES:
Independently oversee and coordinate all activities according to GCP and protocol requirements.
Prepare and execute research plans in liaison with other study teams including international collaborating partners.
Take the lead in/contribute to study/clinical trial set up, identification of resource requirements, documentation of protocols, and staff training and as required.
Supervise and mentor other study team members.
Lead the collection, processing, compilation, and analysis of study data/samples and ensure all related records and reports are handled and managed in line with study protocols.
Prepare, analyse, and present research summaries to Kilifi County public health staff, international collaborators, sponsors and at international conferences and meetings.
Liaise with data management teams to ensure that all data is entered into relevant databases on time and verified.
Carry out data analysis and interpretation and provide relevant matrices/ information including statistics, summaries, charts, graphs, reports, presentations etc.
Prepare and submit draft reports as required including activity reports, project progress reports etc.
Attend and actively participate in investigator’s meetings and other meetings within the research group, department, and programme e.g., journal clubs/seminars as needed.
To participate in manuscript preparation, grant development, among other scientific roles
Support and provide scientific mentorship and supervision of students working in the project.
And any other duties that may be assigned by supervisors from time to time.

QUALIFICATIONS:

PhD in a relevant biomedical subject or any other relevant field.
Undergraduate or Master’s degree in a relevant field.
Up to 4 years postdoctoral experience
Eligibility for registration with the Kenya Medical Practitioners and Dentists Board if clinically trained.
Proven record of experience with human subject’s research or demonstrable active interest and/or experience in biomedical research. Work on clinical trials or observational studies is an added advantage.
Working experience in data analysis and use of statistical analysis software such as STATA or R.
Significant skills in leadership, organisation, prioritisation, problem solving and decision making.
Ability to network, communicate, resolving disputes, and maintain good working relationships within a multi-cultural environment.
Ability to lead and work within a team.

DESIRABLE

Training in ICH-GCP.
Experience/qualification in adult medicine (clinical or research) if clinically trained.
Experience/qualification in basic biostatistics and clinical research.
1-2 years’ experience in clinical trials.
Training in adult life support (basic and/or advanced) if clinically trained.
Current passport and ability to travel for international meetings.

COMPETENCIES:

Demonstrated high levels of confidentiality and integrity.
Excellent interpersonal, written, presentation, and communication skills. 
Excellent analytical, problem-solving, and critical thinking skills.
Strong Management, leadership, and decision-making skills.
Ability to build strong and diverse effective teams, delegation, and team motivation.
Ability to build productive and collaborative relationships with various stakeholders.
Ability to work independently with minimal supervision.

PHYSICAL ENVIRONMENT/ CONDITIONS:

Based at the KEMRI/Wellcome Trust Research Programme in Kilifi and be available to work out of hours where necessary
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